Precision Medicine CanPREVENT AMR: Applying Precision Medicine Technologies in Canada to Prevent Antibody Mediated Rejection and Premature Kidney Transplant Loss

Status

Completed

Grant Name

Genome Canada

Grant Amount

$9,700,000

Researcher(s)

Stirling Bryan
Caulfield , Timothy
Keown, Paul
Sapir-Pichhadze, Ruth
Illustration from research for genomic medicine or gene therapy.

Transplantation is the treatment of choice for patients whose kidneys have failed, providing superior survival, better quality of life and lower health-care system costs (<$20,000/year vs. > $90,000) compared with dialysis. However, a severe form of rejection (known as antibody-mediated rejection, or AMR) causes premature loss of the transplant kidney in as many as 30 per cent of transplant recipients, or 500 Canadians every year, prompting a return to dialysis and often early death.

Related News

Related Publications

Contact Us

Let’s Connect